Topic

#validation

3 posts

2026-08-30

SAS to R Migration in Clinical Programming: A Practical Field Guide

Why pharma is moving from SAS to R, what breaks in practice (procedures, XPT files, QC), and how to migrate a validated macro library without a rewrite.

#sas-to-r #pharmaverse #admiral #clinical-programming #xpt #validation

2026-08-30

One Number That Explains Where Rule-Based Validation Stops

69.7% of oncology CORE rules port cleanly to a graph constraint language. The 30% that don't are exactly where the dangerous errors live.

#cdisc #sdtm #validation #core

2026-08-25

Double Programming Without the Duplication: AI-Generated QC Code

Independent QC re-programming costs 30–50% of clinical programming effort. An AI framework matched 97.1–100% of variables while keeping independence intact.

#qc-programming #clinical-trials #llm-agents #adam #validation