2026-08-30
Temperature 0 Doesn't Buy You Reproducibility
Setting temperature to zero feels like determinism. It isn't — and in GxP work the difference will find you during an audit, not during development.
Topic
#llm
3 posts
2026-08-30
LLMs in Clinical Statistical Programming: Proven vs Hype (2026)
A tiered survey of LLM evidence in clinical trial statistical programming: benchmarked results, promising single-team studies, vendor hype, and open gaps for 2026–2027.
#llm#clinical-trials#statistical-programming#survey#benchmarks#gxp
2026-08-10
Synthetic ADaM That Survives a Join: Knowledge Graphs, LLMs, Faker
Schema-only synthetic ADaM generation plateaus at 0.45 overall quality; enriching schemas from protocol/SAP/CRF knowledge graphs plus templates reaches 0.70.
#synthetic-data#adam#knowledge-graphs#llm#statistical-programming